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February 2021
New imaging tools to decipher neural network dysfunction underlying cognitive deficits in epilepsy
Talk with Dr Peyman Golshani Date: February 9, 2021 5 PM BST, pub chat at 6 PM BST Abstract: Temporal lobe epilepsy is associated with memory deficits but the circuit mechanisms underlying these cognitive disabilities are not understood. We used electrophysiological recordings, open-source wire-free miniaturized microscopy and computational modelling to probe these deficits in a model of temporal lobe epilepsy. We find desynchronization of dentate gyrus interneurons with CA1 interneurons during theta oscillations and a loss of precision and stability of place fields. We also…
Find out more »History of Self Experimentation in Neuroscience
Talk with Dr. Matthew J Lennon Time and date: February 17, 2021 4 P.M. GMT Self-Experimentation has shaped the history of neurological research. Isaac Newton pushed a needle in his eye socket to map out the visual distribution of the retina. Angelo Ruffini resected sensitive parts of his own hand to discover sensory nerve endings, including the Ruffini Corpuscle. Oliver Sacks experimented with morphine to better understand subjective drug effects on patients. Kevin Warwick pioneered prosthetics research when he inserted an electrode array into…
Find out more »March 2021
Cancelled: Talk with Prof Tansu Celikel
Dear all, We regret to inform you that the talk today with Prof Tansu Celikel is cancelled due to unforeseen circumstances. This talk will be rescheduled for a later date, and we will inform you about it as soon as it is arranged. With apologies and best wishes Cortex Club Committee
Find out more »Mini-symposium on neurogenesis and neurodegeneration
Talk with Henrich Sebastian Allard and Peter Kilfeather Date: Tuesday, March 16th, 6PM GMT
Find out more »May 2021
Sleep circuitry: linking homeostasis, sedation and stress
Talk will Professor Bill Wisden Date: May 19, 2021, 4:30 PM GMT Please see the newsletter for the Zoom link. Topic: Sleep circuitry: linking homeostasis, sedation and stress Abstract: There are multiple theories as to why we sleep. I will present our lab's work on what circuitries sense the inexorable drive to sleep when we are sleep-deprived (sleep homeostasis). We are interested in if sedative drugs promote these restorative sleep pathways. I will also talk about powerful new sleep-promoting circuitry we have discovered in the basal ganglia…
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