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Seminar: Prof Oscar Marin
February 12, 2019 @ 16:00 - 17:00
Molecular mechanisms of cortical interneuron diversity and plasticity
Friday 12 February, 4pm at the Large Lecture Theatre, Le Gros Clarke Building, Oxford
The Cortex Club is delighted to presents Prof Oscar Marin from the MRC Centre for Neurodevelopmental Disorders at King’s College London, who will be talking to us about his work diversity and plasticity of cortical interneurons. Please join us on February 12th at the Large Lecture Theatre, located in the Le Gros Clarke Building of the Department of Physiology, Anatomy and Genetics.
Prof Marin has kindly agreed to meet students and staff individually. If you would like to arrange a meeting please contact matthew.buchan – at – chch.ox.ac.uk.
GABAergic interneurons play crucial roles in the regulation of neural circuit activity in the cerebral cortex. A hallmark of cortical interneurons is their remarkable structural and functional diversity, yet the molecular determinants and the precise timing underlying their diversification remain largely unknown. The search for mechanisms controlling the diversity of GABAergic interneurons has primarily focused on the analysis of transcriptional programs in their progenitor cells. In this talk, I will describe how transcriptional programmes, both during embryonic development and in the postnatal brain, regulate the identity of specific classes of cortical interneurons, thereby contributing to the generation of neuronal diversity in the cerebral cortex.