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Seminar: Prof Ileana Hanganu-Opatz
October 29, 2018 @ 16:00 - 17:00
Cognitive ontogeny in health and disease: a story of right communication
Monday 29 October – 4pm at the Large Lecture Theatre, DPAG/Le Gros Clarke Bldg
The Cortex Club is delighted to present Prof Ileana Hanganu-Opatz from the University Medical Center Hamburg-Eppendorf, who will be talking to us about the maturation of the prefrontal-hippocampal networks. Please join us on October 29th at the Large Lecture Theatre, located in the Le Gros Clark Building of the Department of Physiology, Anatomy and Genetics.
There will be drinks and nibbles after the talk. Feel free to join us if you would like to meet Prof Ileana Hanganu-Opatz.
Cognitive performance relies on the entrainment of neuronal networks in oscillatory patterns of electrical activity, as exemplified in the case of functional interplay between the prefrontal cortex and hippocampus. Coupling of neuronal networks in oscillatory rhythms emerges early during development. However, the contribution of coordinated activity for the maturation of neuronal networks remains largely unknown. The talk will introduce the mechanisms controlling the development of structural and functional coupling within prefrontal-hippocampal networks of rodents. Moreover, the dysfunction within hippocampal-prefrontal networks, switching from neonatal hypo- to juvenile hyper-coupling, will be characterized as a possible mechanism underlying the pathophysiology of cognitive deficits in neuropsychiatric disorders.