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Coordinated cerebellar dynamics during goal-directed behaviour
March 9 @ 16:00 - 17:00
Cortex Club Presents: Dr Dimitar Kostadinov
Everyone is welcome to attend this talk at 4pm in the Sherrington Room, Sherrington Building.
The cerebellum facilitates smooth motor execution and learning by constructing internal models that link sensation to action. In addition to this well-studied function, there is increasing evidence for a cerebellar contribution to cognitive processes, such as processing of reward. We aim to understand how sensory, motor, and higher-order parameters are encoded by populations of cerebellar neurons.
To address this question, we use population two-photon calcium imaging and Neuropixels probes to record activity from populations of cerebellar neurons, with a focus on Purkinje cells – the output neurons of the cerebellar cortex. In this talk, I will discuss our recent findings addressing how the climbing fiber pathway conveys both sensorimotor and reward-related signals to Purkinje cells during goal-directed behaviour, and how these signals are shaped by learning.
To join the speaker at the pub, sign up here: https://forms.gle/N2WxchKoagCW6LLq5