What we know and what we don’t know about sleep slow oscillation
Tuesday 22 May @ 4.30pm – 5.30pm (Large Lecture Theatre, Le Gros Clark Building, Department of Physiology, Anatomy and Genetics)
Cortex Club and SCNI present this seminar by Professor Igor Timofeev from the Centre de Recherche Cervo, Université Laval on Tuesday May 22nd at 4.30pm in the Large Lecture Theatre, Le Gros Clark Building, Department of Physiology, Anatomy and Genetics. After the talk we will go to University Club (11 Mansfield Rd) for some food and drinks with the speaker. All university members welcome!
Slow oscillation is a major component of brain electrographic activity during sleep. Descriptively, it is composed of two neuronal states: active and silent. Slow oscillation originates in cortex. Active states start typically in frontal cortex and propagate backward. Silent state onset occurs relatively synchronized across cortical mantle. There are many unresolved questions of origin of slow oscillation: how activity starts when the whole cortex is silent? Which neuronal properties for frontal cortex make it preferential site of origin of propagating active states? Why active states of slow oscillation during slow-waves terminate and terminate nearly simultaneously across large cortical territories, and why they do not terminate during REM sleep or waking state?