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Seminar + Q&A: Professor Tobias Langenhan
June 19 @ 12:00 pm - 1:00 pm
Understanding the molecular logic of Adhesion GPCRs in mechanosensation
Tuesday 19 June @ 12pm – 1pm (Sherrington Room, Sherrington Building, Department of Physiology, Anatomy and Genetics)
On Tuesday June 19th we are excited to be hosting a seminar in partnership with DPAG by Professor Tobias Langenhan from the Rudolf Schönheimer Institute of Biochemistry at Leipzig University. The talk will take place in the Sherrington Room, Sherrington Building, Department of Physiology, Anatomy and Genetics. The talk will be followed by a free Q&A lunch with the speaker at 1pm in the Sherrington Library. If you would like to join for the Q&A, please sign up by e-mailing us at cortex.club -at- studentclubs.ox.ac.uk. You can also contact Professor Maike Glitsch (maike.glitsch -at- dpag.ox.ac.uk) if you would like to arrange an individual meeting with the speaker.
G protein-coupled receptors (GPCR) have proven a treasure trove for the modern pharmacological intervention of numerous human ailments. However, in stark contrast to classically targeted GPCRs, adhesion GPCRs have been largely neglected by biologists, pharmacologists and clinician scientists for decades. Only recently their physiological and signalling properties are being unravelled and show exciting features including their roles in tissue architecture, signalling through tethered agonism and their unusual activation through mechanical cues. This seminar will discuss the recent developments on adhesion GPCR signalling and introduce the receptor family as a topical area in neuroscience and cancer research.